New Hip Replaced Due to Infection and Now Its Infected Again

A police officeholder wearing personal protective equipment in Manzhouli, Prc
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Latest coronavirus news as of 12pm 16 March
Covid-xix is surging in Cathay, with more than 5000 new cases a twenty-four hours
China yesterday reported 5280 new SARS-CoV-2 cases, more than double the previous day'south count and its highest daily tally since the start of the pandemic. The surge has prompted the introduction of full or fractional lockdowns in various cities across the country.
Red china has been pursuing a strict 'zero covid' strategy, which until recently had largely kept outbreaks nether control. The omicron variant, however, is more transmissible than previous variants and is probably driving the current surge.
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Cities across the state are now in full or partial lockdowns. The north-eastward province Jilin is the worst afflicted, accounting for more 3000 of China's new reported cases on 15 March. Speaking on 14 March, Jilin'southward governor vowed to "accomplish community zero-Covid in a calendar week".
China's rising cases correspond with a global increase in SARS-CoV-2 transmission. A World Health Organization report reveals the number of new reported infections between seven and 13 March increased by eight per cent compared to the previous week. The number of new weekly cases had been declining since the finish of Jan.
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Face covering rules in Scotland will remain in identify until Apr. On 15 March, Scotland reported 38,770 new covid cases, upward from a daily average of 6,900 3 weeks agone. As a result, coverings will proceed to be required on public transport and in shops, although other covid restrictions will be lifted on 21 March. The BA.2 omicron sublineage, which is fifty-fifty more transmissible than the initial omicron variant, accounts for 80 per cent of Scotland'southward SARS-CoV-2 cases, according to showtime government minister Nicola Sturgeon, who added it is "prudent" to keep mask rules in place. A small study has linked covid-19 with cardiovascular changes amidst unvaccinated people without whatsoever pre-existing medical weather. Fábio Santos de Lira from São Paulo State Academy and his colleagues looked at 38 people, aged twenty to twoscore, less than half-dozen months after they were infected with SARS-CoV-2. Even mild or moderate infections were linked to cardiovascular changes that resulted in a raised heart rate, which affected some of the participants's power to climb stairs or walk.
Essential data about coronavirus
Where did coronavirus come up from? And other covid-19 questions answered
What is covid-19?
Covid-nineteen vaccines: Everything you need to know nearly the leading shots
Long covid: Do I accept information technology, how long will information technology last and can we treat it?
What's the fairest fashion to share covid-nineteen vaccines around the world?
Covid-xix: The story of a pandemic
What to read, watch and listen to about coronavirus
New Scientist Weekly features updates and analysis on the latest developments in the covid-nineteen pandemic. Our podcast sees expert journalists from the magazine discuss the biggest science stories to hit the headlines each calendar week – from technology and space, to health and the surroundings.
The Bound is a BBC Radio 4 serial exploring how viruses tin cross from animals into humans to cause pandemics. The first episode examines the origins of the covid-nineteen pandemic.
Why Is Covid Killing People of Color? is a BBC documentary, which investigates what the high covid-xix death rates in ethnic minority patients reveal nearly health inequality in the Uk.
Panorama: The Race for a Vaccine is a BBC documentary nigh the inside story of the development of the Oxford/AstraZeneca vaccine against covid-nineteen.
Race Against the Virus: Chase for a Vaccine is a Aqueduct 4 documentary which tells the story of the coronavirus pandemic through the eyes of the scientists on the frontline.
The New York Times is assessing the progress in evolution of potential drug treatments for covid-19, and ranking them for effectiveness and rubber.
Humans of COVID-19 is a project highlighting the experiences of cardinal workers on the frontline in the fight against coronavirus in the U.k., through social media.
Belly Mujinga: Searching for the Truth is a BBC Panorama investigation of the decease of ship worker Belly Mujinga from covid-xix, following reports she had been coughed and spat on by a customer at London'due south Victoria Station.
Coronavirus, Explained on Netflix is a curt documentary serial examining the coronavirus pandemic, the efforts to fight it and ways to manage its mental wellness toll.
Stopping the Adjacent Pandemic: How Covid-19 Tin can Help Us Salvage Humanity by Debora Mackenzie is almost how the pandemic happened and why it volition happen again if we don't do things differently in hereafter.
The Rules of Contagion is about the new science of contagion and the surprising ways it shapes our lives and behaviour. The author, Adam Kucharski, is an epidemiologist at the London School of Hygiene and Tropical Medicine, Uk, and in the volume he examines how diseases spread and why they stop.
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Commuters leave a London Overground train, Liverpool Street, London
AFP via Getty Images
14 March
Nearly 400,000 people in the UK tested positive for the coronavirus terminal week
Government statistics testify 399,820 people tested positive for SARS-CoV-2 in the UK between v and 11 March, an increment of 143,956 (56.3 per cent) on the previous vii days. Between 1 and 7 March, hospitalisations increased by 16.9 per cent from the previous week. Deaths within 28 days of a positive test are rise more slowly, with a week-on-week increase of 2.8 per cent as of xi March. Easing restrictions, waning immunity and the more than transmissible omicron sublineage BA.2 are thought to be driving the surge in cases.
Amongst the rise in infections, ministers have been criticised for scrapping England'south React study at the end of March. React randomly tests about 150,000 people across the country for SARS-CoV-2 each month to gauge nationwide infection levels. Talking to The Guardian, one scientist called the movement "about every bit far from 'following the science' as you can go", while another accused ministers of "turning off the headlights at the start sight of dawn".
Ministers are too beingness urged to consider offering older people a 4th vaccine dose. In England, people with a suppressed immune organization, living in a intendance home or aged 75 or older are set to exist offered an additional jab in April. Some scientists are calling for the age requirement to be set lower. However, a modest Israeli written report of healthcare workers found a fourth dose increased some antibody levels, but this did not translate into boosted immunity.
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Cathay'southward covid-19 cases accept doubled in 24 hours amid its worst outbreak in two years. Nearly 3400 new cases were reported on xiii March, double the previous mean solar day. This has prompted schools to close in Shanghai, China's biggest urban center, and regional lockdowns to exist introduced in several north-eastern hotspots. The surge in cases is idea to be driven by omicron and a ascension in asymptomatic infections.
Latest on covid-nineteen from New Scientist
Many countries have scaled dorsum their coronavirus restrictions, just Iceland is going further with a plan to let infections spread

Laboratory culture system using VeroE6 cells tested negative for covid-xix.
Rockett et al, 2022
10 March
The monoclonal antibiotic sotrovimab has been linked to a drug-resistant mutation in SARS-CoV-2.
A study in Australia suggests that sotrovimab, a treatment for covid, may cause the coronavirus to larn mutations that enable it to resist the drug.
Sotrovimab neutralises SARS-CoV-2's fasten protein, which the virus uses to enter cells. Given through a baste, sotrovimab can exist administered to people within five days of their infection to prevent symptoms from condign severe.
Rebecca Rockett from the University of Sydney and her colleagues reviewed the first 100 people who received sotrovimab at a healthcare facility in New South Wales between August and November 2021, when the delta variant of the virus was dominant. Eight of the people who were treated persistently tested positive for SARS-CoV-ii, and had airway samples collected before and after they received sotrovimab.
In four of these patients, SARS-CoV-2 developed spike mutations betwixt six and xiii days subsequently sotrovimab was administered, with these genetic changes making the drug 'finer inactive', said Rockett, as reported in The Guardian.
The researchers are calling for increased genomic surveillance effectually sotrovimab'southward utilize. "What we don't want to see is resistant virus disseminating in the community, considering that will hateful that a lot of other people can't employ this drug every bit well," said Rockett.
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The WHO has warned the pandemic is "far from over". The number of global recorded deaths betwixt 28 February and half dozen March declined by 8 per cent compared to the previous week, with recorded infections too falling by 5 per cent. "Although reported cases and deaths are declining globally, and several countries have lifted restrictions, the pandemic is far from over – and it will not exist over anywhere until it's over everywhere," Tedros Adhanom Ghebreyesus, WHO's director-general, said on 9 March. "The virus continues to evolve, and nosotros continue to face major obstacles in distributing vaccines, tests and treatments everywhere they are needed."
A surveillance program that looks for SARS-CoV-2 in wastewater has been rolled out across Northern Ireland, the BBC reported. Wastewater samples from 31 sites are beingness nerveless every day and sent to a Queen's University Belfast laboratory for testing. Gauging infection levels in specific areas may help to prevent big SARS-CoV-2 outbreaks, with the engineering science also looking for new variants.

Students queuing up for covid-19 nucleic acid tests, Qingdao, Shandong province, Prc
Wei Zhe/VCG via Getty Images
9 March
Covid deaths and new infections are continuing to decline after the peak of the omicron surge
The number of global recorded covid deaths between 28 February and half dozen March declined past 8 per cent compared to the previous week. In its weekly update, the WHO reported the number of recorded new SARS-CoV-2 infections also decreased by 5 per cent week-on-week.
In the week starting 28 February, more than 10 1000000 new covid cases and 52,000 deaths were reported across the WHO'south six regions.
Case numbers only increased in the Western Pacific Region, rising by 46 per cent. Covid deaths rose in the Western Pacific and Eastern Mediterranean regions, by 29 per cent and ii per cent, respectively, with fatalities falling elsewhere.
The surge in infection caused by the omicron variant appears to have peaked in February. Merely the WHO has stressed that countries vary in their testing strategies and therefore whatsoever trends should be interpreted with circumspection.
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However, in the UK, reported coronavirus cases have increased by nearly two-fifths week-on-week. According to government information,322,917 people reported a positive test between 2 and viii March, an increase of 90,944 (39.2 per cent) from the previous week. Hospital covid admissions are besides rising, with 8763 people admitted between 26 February and four March, an increase of 11.1 per cent from the previous week. Deaths have slightly declined, however. Between 2 and 8 March, 729 people died within 28 days of a positive test, 12 (i.6 per cent) fewer than the previous week.
The number of cancer enquiry studies funded in the Britain fell by 32 per cent in the get-go yr of the pandemic, according to figures from the National Cancer Research Institute. The money awarded to these projects plunged by 57 per cent, The Guardian reports. The endmost of charity shops and cancelled fundraising events are idea to accept contributed to the problem.

Covid-xix booster jab data campaign, Putney, London, Uk
Amer Ghazzal/Shutterstock
7 March
Booster jabs substantially increased protection against omicron but efficacy starts to fall after two months
The protection given past vaccine booster shots confronting the omicron variant starts to pass up after two months, a study has found.
Researchers at the UK Health Security Agency looked at covid-19 infections in the UK betwixt 27 November 2021 and 12 January 2022 – the period in which the omicron variant started to spread widely. The information included over one meg people who had been infected with either the delta or omicron variant.
The researchers merely looked at whether people adult a mild illness and non whether someone was hospitalised or non.
They establish that a booster dose substantially increased protection against developing mild illness from the omicron variant. Two doses of the Pfizer/BioNTech vaccine were only 8.8 per cent constructive against the omicron variant after 25 or more weeks. But a third booster dose of this vaccine increased protection to 67.ii per cent. However, this and so dropped to 45.vii per cent after 10 or more weeks.
A Moderna booster, given to those who had received two initial doses of the Pfizer jab, was 73.nine per cent effective against mild disease from the omicron variant later two to iv weeks. This then dropped to 64.four per cent after five to nine weeks.
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Red china logged its highest daily number of symptomatic coronavirus infections in two years yesterday. China reported 214 domestically transmitted cases with confirmed symptoms on Lord's day – it is the nation'southward highest number of cases recorded in a single solar day since March 2020.
The global recorded decease toll from covid-19 has passed half-dozen million. The price, compiled past Johns Hopkins University, stood at 6,000,394 as of Monday midday.
This number is likely to exist a gross underestimate of how many people have actually died from the virus globally. This is due to poor reporting and testing mechanisms in many parts of the world.

Baricitinib
Felipe caparros cruz/Alamy
4 March
Immune-suppressing treatment reduces deaths even in people already taking existing covid-19 medicines
Some other treatment has been shown to aid people hospitalised with severe covid-nineteen: an arthritis medicine chosen baricitinib, which works by dampening the allowed response. In the later stages of covid-19, overactivity of the allowed system contributes to damage to the lungs and the blood clotting system, which causes tiny blood clots to class throughout the body.
Baricitinib was already existence used in some countries, but a big UK trial has now shown that calculation it to the other treatments used against covid-19 further reduces the death charge per unit by thirteen per cent. Most people in the study were already being given the steroid treatment dexamethasone, the first medicine shown to reduce deaths in covid-19, which also suppresses the inflammatory allowed reaction. When this result is combined with other trials, it suggests baricitinib could reduce deaths by 1 5th.
Baricitinib works by blocking the actions of an immune system compound called interleukin-six (IL-6), which is raised in severe covid-nineteen. It comes in tablet form, making it easier to requite than another IL-6-blocking medicine chosen tocilizumab, given through a baste. About a third of people in the trial likewise received tocilizumab and they still had the boosted reduction in deaths from baricitinib.
"As an oral agent with a short one-half-life and potentially less expensive, this makes baricitinib a more attractive agent afterwards steroids in depression/heart-income country settings," said Athimalaipet Ramanan, at the University of Bristol, UK, in a statement.
Other coronavirus news
Panic buying has begun in Hong Kong amid fears of an impending lockdown, as cases of covid-nineteen and deaths due to the virus are soaring. The city, which is in the centre of an omicron surge, has relatively depression vaccination rates amid its elderly. 2 of Hong Kong's largest retail chains take started rationing some nutrient and medicines.
Measuring fourteen proteins in the blood can help predict if people will get severe covid-xix, according to a study that used a genetic technique called Mendelian randomisation to link people's genes with their risk of illness. The study found half-dozen proteins that crusade higher rates of hospitalisation or death and eight that protect against such outcomes. One of the risky proteins determines a person's blood group, supporting previous studies that have suggested people with blood group A are more probable to exist admitted to infirmary with covid-19.

A adult female waters plants in her firm
Samuel de Roman/Getty Images
3 March
Pandemic linked to increase in depression and anxiety worldwide
A World Health Organization (WHO) briefing suggests that depression and anxiety accept risen substantially during the coronavirus pandemic, with women and young people amidst the worst affected.
Based on a review of existing evidence into covid-19's impact on mental health, the conference largely attributes the rise to the unprecedented stress of social isolation, also as grieving loved ones, financial worries and fright of infection.
Most of the countries surveyed (ninety per cent) have included mental health back up in their covid-19 recovery plans, however, the WHO has stressed there are yet gaps in care.
"The information we have now almost the bear upon of covid-nineteen on the earth'south mental health is but the tip of the iceberg," said WHO's Tedros Adhanom Ghebreyesus, in a statement. "This is a wake-up telephone call to all countries to pay more attention to mental health and do a improve job of supporting their populations' mental health."
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The WHO has conditionally recommended molnupiravir every bit the start oral antiviral drug for people with non-severe covid who are most at risk of hospitalisation, such as older age groups or people who are immunocompromised. The recommendation is based on six studies with a full of 4796 participants between them. The review institute that, when given inside five days of the onset of mild symptoms, administering iv molnupiravir tablets twice a solar day for five days can reduce the risk of hospitalisation by 30 per cent.
Covid restrictions are thought to accept resulted in there being 720,000 fewer dengue fever infections in 2020 than would normally exist expected. The team behind the work were surprised by their findings, having anticipated that rates of the mosquito-transmitted infection would take risen when people were forced to spend more time at home. The latest results, published in The Lancet Infectious Diseases, contradict previous research by a different team, who warned that an additional 2008 dengue cases may have occurred a month in Thailand among its 2020 restrictions.
The pandemic may exist intensifying pre-existing inequalities between the sexes. US researchers reviewed datasets on issues like healthcare access, economic concerns and safety for 193 countries between March 2020 and September 2021. They establish girls were i.21 times more probable to have dropped out of school than boys, while women were 1.23 times more than likely to report an increase in gender-based violence than their male counterparts.

In vitro fecundation
Mike Kiev/Alamy
2 March
A report of 43 countries suggests the coronavirus pandemic has substantially pushed back fertility treatments, with Scotland facing some of the biggest delays.
A team involving researchers at Monash University, Australia, sent surveys to fertility clinics across Asia, Africa, Europe, North America and Due south America from October 2020 to September 2021.
Treatment delays were reported in 34 countries, with people waiting an boilerplate of 59 days for IVF or an intracytoplasmic sperm injection, when a single sperm is inserted into an egg in a laboratory. Frozen embryo transfers were delayed by an average of sixty days. These occur when embryos from a previous IVF cycle are thawed and inserted into the womb.
The study, which is due to be published in Reproductive Medicine, found that the largest delay in fertility treatments was 228 days, reported by a clinic in Scotland. Austria, China, Germany, Hong Kong, Norway and Portugal were the merely countries where the clinics surveyed reported no delays.
On nineteen March 2020, the European Guild for Human Reproduction and Embryology advised people to avoid procedures similar IVF due to dubiety around how the coronavirus affected pregnancies. Ii days earlier, the American Society for Reproductive Medicine announced a "filibuster (to) any but the nearly important care cases".
"The need to stop or delay treatment was guided by the uncertainty of the virus, and the [need] to reduce the brunt of non-essential medical treatments in hospitals to allow resources to exist allocated to dealing with people with COVID-19", said Elizabeth Cutting, at Monash Academy, in a statement.
"While there was advice regarding virus exposure and manual, at that place was a compatible lack of advice regarding the provision of psychological support and how to prioritise patients".
Other coronavirus news
Compulsory coronavirus vaccines for care habitation staff are existence scrapped in England from 15 March. The policy previously required anyone working in a Intendance Quality Commission-registered care habitation to accept 2 vaccine doses, unless medically exempt. Amid fears of a staffing crisis, the government has said public immunity to the coronavirus is now high due to widespread vaccine uptake and many people recovering from the omicron variant.
Nerve damage may play a function in some cases of long covid. A small study of 17 people experiencing long-term symptoms found that 59 per cent had signs of nerve damage, possibly acquired by an overactive immune response. "I remember what'due south going on here is that the nerves that control things like our breathing, blood vessels and our digestion in some cases are damaged in these long COVID patients," said neurologist Anne Louise Oaklander, reported by Reuters.
Preliminary laboratory studies suggest that modified T-cells could assistance treat covid in people on allowed-suppressing drugs. Researchers in Germany genetically modified the T-cells of people who had recovered from covid-19 to brand them resistant to the drug tacrolimus, which is unremarkably given to people who have had an organ transplant to foreclose rejection. The modified cells then attacked the coronavirus while exposed to tacrolimus in a laboratory experiment.

A child receives a dose of Pfizer/BioNTech covid-19 vaccine
Alexandre Schneider/Getty Images
1 March
Study suggests that protection from two doses of the Pfizer/BioNTech covid-19 vaccine speedily wanes in children betwixt five and eleven
Protection confronting infection and hospitalisation from the Pfizer/BioNTech covid-nineteen vaccine falls relatively quickly in children aged 5 to 11, according to a preliminary study.
Researchers analysed covid-xix cases and hospitalisations amid 365,502 fully vaccinated children aged betwixt five to 11, and 852,384 anile between 12 and 17, all of whom lived in New York. They looked at data from 13 December 2021 to 30 January 2022, during a surge of covid-19 infections from the omicron variant.
The team constitute that, for the older children, the Pfizer/BioNTech vaccine'due south protection against hospitalisation fell from 85 per cent in mid-December to 73 per cent by the end of January. But the drop was steeper for children aged five to 11, with protection against hospitalisation declining from 100 per cent to only 48 per cent.
For protection against infection, effectiveness dropped from 66 per cent to 51 per cent amongst the 12 to 17 historic period group, and from 68 per cent to 12 per cent in the younger age group.
Florian Krammer, at Mount Sinai's Icahn School of Medicine, told the New York Times: "The difference between the two age groups is striking,"
Those in the younger historic period grouping receive a 10 microgram dose of the vaccine, compared with 12 to 17-twelvemonth-olds who receive a 30 microgram dose, which could explicate some of the discrepancy in the vaccine's effectiveness over time.
Other coronavirus news
Researchers may have found a case of deer-to-man covid-xix manual in Canada. In a preliminary study published on 25 February, the team traced at to the lowest degree i example of covid-19 in humans back to a strain of the virus plant in white-tailed deer.
White-tailed deer had previously been found to be infected with covid-19 in the U.s. and Canada. For the study, the researchers took samples from hunted deers in Ontario, Canada and found 17 were infected with a previously unknown strain of covid-19.
They then found that i person, who had been in contact with deer, had tested positive for similar strain.
Hong Kong today reported 32,597 new infections and 117 deaths – the metropolis'southward highest figure since the pandemic began. The city has seen a huge surge in covid-19 cases, with merely 739 new cases on ane February. Hong Kong'south fatality rate is currently one of the highest in the world, which may partly exist due to lower vaccination rates in older age groups. To tackle the electric current surge, the city plans to brainstorm mass testing its 7.4 million residents in mid-March.
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Source: https://www.newscientist.com/article/2237475-covid-19-news-uk-data-reveals-56-per-cent-rise-in-recorded-cases/
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